Research Interests

 The main goal of the department is the study of the spinal and supraspinal structures involved in the control of nociception and autonomic functions.

The department is composed of three research groups, the identity of which is based on technical approaches specific to different analysis levels, from the single cell to the whole organism. The laboratory studies the mechanisms of transmission and modulation of nociceptive information at all levels of the central nervous system (sensory neurons, spinal cord, brain) aiming at understanding how the feeling of pain is elaborated, as well as the associated autonomic, emotional and behavioural responses. Studies are carried out in mature or developing systems, in situations of neurogenic or inflammatory pain subject to evolution toward states of chronic pain. Co-transmissions (GABA / ATP; GABA / Glycine) in the nociceptive neuronal networks of the spinal cord are particularly studied, as well as modulation mechanisms involving other endogenous molecules (neuropeptides and neurosteroids).

Head of Department

Rémy SCHLICHTER

Contact

INCI - UPR 3212

Département Nociception & douleur

21 rue René Descartes

F- 67084 Strasbourg Cedex

Tél. : +33 (0)3 68 85 14 40

Fax. : +33 (0)3 88 61 33 47