Boulenguez P, Liabeuf S, Bos R, Bras H, Jean-Xavier C, Brocard C, Stil A, Darbon P, Cattaert D, Delpire E, Marsala M, Vinay L
Down-regulation of the potassium-chloride cotransporter KCC2 contributes to spasticity after spinal cord injury. Nat Med, 2010 Mar, 16(3): 302-307

Vitale N
Synthesis of fusogenic lipids through activation of phospholipase D1 by GTPases and the kinase RSK2 is required for calcium-regulated exocytosis in neuroendocrine cells. Biochem Soc Trans, 2010 Feb, 38(Pt 1): 167-71

Poulain B
La neurotoxine botulinique [Botulinum neurotoxin]. Rev Neurol (Paris), 2010 Jan, 166(1): 7-20

Seminar: Dysfunctions and recovery in a transgenic model of Alzheimer's disease-like Tau pathology - David Blum (Lille)

March 18 - 11:00 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Brain Awareness Week

Events to educate and inform people of all ages about the brain and brain research

> Programme in Alsace

March 4-25 in Strasbourg and Mulhouse

HDR: Retinocollicular map formation: from biology to mathematics - Michaël Reber

February 26 - 14:00 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Seminar: Synaptic and non synaptic roles of neural activity in sculpting retinal projections - Patricia Gaspar (Inserm U.839, Paris)

February 26 - 10:30 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Seminar: Establishing the functional circuitry in the vertebrate visual system - Robert Hindges (King's College, London)

February 25 - 14:00 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Thesis: La queue GABAergique de l’aire tegmentale ventrale : un nouveau centre de contrôle des systhèmes dopaminergiques - Jennifer Kaufling

February 26 - 13:30 - IPCB, 21 rue René Descartes, Strasbourg

Mendoza J, Pévet P, Felder-Schmittbuhl MP, Bailly Y, Challet E
The cerebellum harbors a circadian oscillator involved in food anticipation. J Neurosci, 2010 Feb 3, 30(5): 1894-904

Bolborea M, Ansel L, Weinert D, Steinlechner S, Pévet P, Klosen P
The bed nucleus of the stria terminalis in the Syrian hamster (Mesocricetus auratus): absence of vasopressin expression in standard and wild-derived hamsters and galanin regulation by seasonal changes in circulating sex steroids. Neuroscience, 2010 Feb 3, 165(3): 819-830

Hanon EA, Routledge K, Dardente H, Masson-Pévet M, Morgan PJ, Hazlerigg DG
Effect of photoperiod on the thyroid-stimulating hormone neuroendocrine system in the European hamster (Cricetus cricetus). J Neuroendocrinol, 2010 Jan, 22(1): 51-5

Glattard E, Welters ID, Lavaux T, Muller AH, Laux A, Zhang D, Schmidt AR, Delalande F, Laventie B-J, Dirrig-Grosch S, Colin DA, Van Dorsselaer A, Aunis D, Metz-Boutigue M-H, Schneider F, Goumon Y
Endogenous Morphine Levels Are Increased in Sepsis: A Partial Implication of Neutrophils. PLoS One, 2010 Jan 20, 5: e8791

Kaufling J, Veinante P, Pawlowski S, Freund-Mercier MJ, Barrot M
gamma-Aminobutyric acid cells with cocaine-induced DeltaFosB in the ventral tegmental area innervate mesolimbic neurons. Biol Psychiatry, 2010 Jan 1, 67: 88-92

Yalcin I, Tessier LH, Petit-Demoulière N, Waltisperger E, Hein L, Freund-Mercier MJ, Barrot M
Chronic treatment with agonists of beta2-adrenergic receptors in neuropathic pain. Exp Neurol, Jan 2010, 221: 115-121

Seminar: GABAA-mediated excitability in the first steps of integration of newborn neurons to the olfactory bulb - Sheyla Mejia Gervacio (Université Paris V)

January 28 - 11:00 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

De Roo M, Boué-Grabot E, Schlichter R
Selective potentiation of homomeric P2X2 ionotropic ATP receptors by a fast non-genomic action of progesterone. Neuropharmacology, 2009 Dec 16 [Epub ahead of print]

Pfrieger FW
Role of glial cells in the formation and maintenance of synapses. Brain Res Rev, 2009 Nov 18 [Epub ahead of print]

Aouad M, Charlet A, Rodeau JL, Poisbeau P
Reduction and prevention of vincristine-induced neuropathic pain symptoms by the non-benzodiazepine anxiolytic etifoxine are mediated by 3alpha-reduced neurosteroids. Pain, 2009 Dec 15, 147(1-3):54-9

Ljubicic S, Bezzi P, Vitale N, Regazzi R
The GTPase RalA regulates different steps of the secretory process in pancreatic beta-cells. PLoS One, 2009 Nov 5, 4(11):e7770

Nexon L, Poirel VJ, Clesse D, Pévet P, Raison S
Complex regional influence of photoperiod on the nycthemeral functioning of the dorsal and median raphé serotoninergic system in the Syrian hamster. Eur J Neurosci., 2009 Nov, 30(9):1790-801

Boudard DL, Mendoza J, Hicks D
Loss of photic entrainment at low illuminances in rats with acute photoreceptor degeneration. Eur J Neurosci., 2009 Oct, 30(8):1527-36

Workshop: Deep brain stimulation: new insights and alternatives

> Program and Subscription

January 26 - Forum, faculté de médecine, Université de Strasbourg

Seminar: OpenElectrophy: an electrophysiological data- and analysis-sharing framework - Samuel Garcia (UMR 5020, Lyon)

January 13 - 11:00 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Buard I, Steinmetz CC, Claudepierre T, Pfrieger FW
Glial cells promote dendrite formation and the reception of synaptic input in Purkinje cells from postnatal mice. Glia, 2009 Nov 11 [Epub ahead of print]

Ljubicic S, Bezzi P, Vitale N, Regazzi R
The GTPase RalA regulates different steps of the secretory process in pancreatic beta-cells. PLoS One, 2009 Nov 5, 4(11):e7770

Claudepierre T, Paques M, Simonutti M, Buard I, Sahel J, Maue RA, Picaud S, Pfrieger FW
Lack of Niemann-Pick type C1 induces age-related degeneration in the mouse retina. Mol Cell Neurosci., 2009 Oct 31 [Epub ahead of print]

Seminar: The challenge of breeding at intermediate day lengths: integrating photic and non-photic cues - Matthew Paul

December 17 - 11:00 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Seminar: Le NAADP et son enzyme de synthèse, l’ecto-enzyme CD38, dans la fonction de sécrétion - José-Manuel Cancela (CNRS UPR 9040, Gif-sur-Yvette)

December 11 - 11:00 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Seminar : Deafness related mutations in Connexin26 gene unveil fundamental domain for the assembly and function of connexin channels - Agustin Martinez (Valparaiso, Chili)

December 3 - 11:00 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Seminar: "Neurophotonique" : développement de nouvelles méthodes optiques pour des études cellulaires et moléculaires in situ - Yves De Koninck (Université Laval Robert-Giffard, Canada)

November 20 - 14:30 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Seminar: Unraveling Synapse Specificity using genetically modified mice - Fekrije Sélimi (The Rockefeller University, New York)

November 12 - 11:00 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Doctoral position

Do melatonin and agomelatin induce an increase in the amplitude of circadian clock oscillations? Physiological and molecular studies.

Thesis: Mécanisme d’action de la toxine epsilon de Clostridium perfringens dans le système nerveux central - Etienne Lonchamp

October 23 - 14:30 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Thesis: Régulation photopériodique du fonctionnement journalier des neurones sérotoninergiques du raphé dorsal et médian chez le hamster doré - Laurent Nexon

October 20 - 13:30 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Thesis: Théorie synaptique du retard mental. Analyse systématique et comparative à l'échelle de la synapse de cinq mutations monogéniques associées au retard mental - Frédéric Gambino

October 9 - 14:00 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Thesis: Role of glial release in mouse retinal development and function - Aurore Niemec

October 2 - 14:30 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Seminar: Connexin-mediated astroglial networks: properties and role in neuroglial interactions - Christian Giaume (Collège de France, Paris)

October 1 - 14:30 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Call for Neurex Postdoctoral fellowships

Neurex supports the cross boarder collaboration in Neuroscience within its network by offering fellowships awarded to scientific projects.

> More information

Seminar: Oxytocin, pain, and childbirth - James Eisenach (Wake Forest University School of Medicine, Winston-Salem)

September 24 - 09:30 - IPCB, 21 rue Descartes - Strasbourg

Seminar: Djungarian hamsters with non-entrained activity onset – a model to study photic entrainment? - Dietmar Weinert (Universität Halle-Wittenberg)

October 8 - 16:00 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Teaching: Electrophysiology Summer School

> Programme

September 21 - 26 - IPCB, 21 rue Descartes - Strasbourg

Lectures: "Défis et innovation en Neurosciences"
[Lectures in English]

September 22 - 23 - Collège Doctoral Européen, 46 Bld de la Victoire, Strasbourg

Thesis: Exploration fonctionnelle de la douleur et de sa modulation spinale chez le rongeur - Alexandre Charlet 

September 28 - 10:00 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Seminar: Mise en place et maintien de réservoirs latents du VIH-1 dans le système nerveux central : aspects moléculaires et implications thérapeutiques - Olivier Rohr

July 16, 14:30 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Humeau Y, Gambino F, Chelly J, Vitale N
X-linked mental retardation: focus on synaptic function and plasticity. J Neurochem., 2009 Apr; 109(1):1-14

Yalcin I, Charlet A, Freund-Mercier MJ, Barrot M, Poisbeau P
Differentiating thermal allodynia and hyperalgesia using dynamic hot and cold plate in rodents. J Pain 10:767-773

Thesis: Structural, functional and behavioural effects of induced retinal degenrations in rod- and cone-rich rodents - Domitille Boudard

June 23, 14:00 - amphi Vlès, IPCB, 21 rue Descartes, Strasbourg

Thesis: Transformation de cellules souches neurales en cellules souches cancéreuses de glioblastome. Rôle de la voie Delta-Notch - Anne-Sophie Laurenson

June 03, 14:00 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Training: Electrophysiology Summer School

September 21 - 26 - Strasbourg

Deadline for inscription: July 18 2009

Neurex annual Meeting: Cognition Plasticity Disease

June 19 - Pôle API, Strasbourg-Illkirch

Seminar: Regulated exocytosis in neuroendocrine cells: MyRIP and Myosin Va control docking of secretory granules to the plasma membrane - Claire Desnos (Paris)

April 29, 15:00 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Thesis: Dynamique des lipides aux cours du cycle d'exo-endocytose dans les cellules neuroendocrines : rôle des protéines Rac1 et scramblase - Fanny Momboisse

April 30, 14:30 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Neurex-SEISC Meeting: Blood Brain interfaces

April 24-25 - IPCB, 21 rue René Descartes, Strasbourg

Seminar: Analyse à haut contenu en cytométrie en flux en pharmacologie - Christian Muller (Faculté de Pharmacie, Strasbourg)

April 9, 11:00 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Seminar: Gliotransmission? A fresh look on vesicular glutamate release from cortical astroglia - Martin Oheim (Paris)

March 26, 11:15 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Momboisse F, Lonchamp E, Calco V, Ceridono M, Vitale N, Bader MF, Gasman S
{beta}PIX-activated Rac1 stimulates the activation of phospholipase D, which is associated with exocytosis in neuroendocrine cells. J Cell Sci., 2009 Mar 15, 122(Pt 6):798-806

Ulmann L, Rodeau JL, Danoux L, Contet-Audonneau JL, Pauly G, Schlichter R
Dehydroepiandrosterone and neurotrophins favor axonal growth in a sensory neuron-keratinocyte coculture model. Neuroscience, 2009, 159: 514–525

Nieweg K, Schaller H, Pfrieger FW
Marked differences in cholesterol synthesis between neurons and glial cells from postnatal rats. J Neurochem., 2009 Feb 20

Disse J, Vitale N, Bader MF, Gerke V
Phospholipase D1 is specifically required for regulated secretion of von Willebrand factor from endothelial cells. Blood, 2009 Jan 22, 113(4):973-80

Performance:

Effervescience dans l'Union Neuropéenne (presented in French) - by Doctoneuro

March 18, 20:00 - Munsterhof, 9 rue des Juifs, Strasbourg

Conference:

Tout ce que vous voulez savoir sur la mélatonine et les rythmes biologique sans oser le demander (presented in French) - Paul Pévet

March 10, 13:30 - délégation Alsace du CNRS, amphi Perey, 23 rue du Loess, Strasbourg

Popoff M, Carlier JP, Poulain B
Botulisme. EMC (Elsevier Masson SAS, Paris), Maladies infectieuses, 8-038-H-50, 2009

Conferences:

Le sommeil et l’hypersomnie (presented in French) - Patrice Bourgin

March 5, 18:00 - amphithéâtre Fresnel, 3 rue de l'Université, Strasbourg

Quand le cerveau hiberne (presented in French) - André Malan

March 12, 18:00 - amphithéâtre Fresnel, 3 rue de l'Université, Strasbourg

Seminar: Wiring diagrams of the suprachiasmatic nucleus - Rae Silver (Columbia University, New York, USA)

March 4, 11:00 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Congress: XI Congress of the European Biological Rhythms Society, organized in association with the Japanese Society for Chronobiology

August 22 - 28 - Strasbourg

Workshop: ETOX 14 - European Workshop on Bacterial Protein Toxins

June 27 - July 02 - Obernai

Thesis: Caractérisation des processus rythmiques dans la rétine d'un rongeur diurne Arvicanthis ansorgei : un nouveau modèle animal d'étude de la physiopathologie des photorécepteurs de type cône (presented in French) - Corina Bobu

February 17, 14:30 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Seminar: Mécanismes de plasticité structurale au sein de l'horloge circadienne (presented in French) - Olivier Bosler (CNRS & Universités Aix-Marseille)

February 13, 11:00 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Thesis: Modulation sérotonergique différentielle de l'horloge circadienne principale entre rongeurs diurnes et nocturnes (presented in French) - Marc Cuesta

February 13, 14:00 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Seminar: Neuronal-glial-endothelial interactions and cell plasticity in the postnatal hypothalamus: implications for the neuroendocrine control of reproduction - Vincent Prévot (Lille)

February 10, 16:00 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Momboisse F, Ory S, Calco V, Malacombe M, Bader MF, Gasman S
Calcium-regulated Exocytosis in Neuroendocrine Cells: Intersectin-1L Stimulates Actin Polymerization and Exocytosis by Activating Cdc42. Ann N Y Acad Sci. 2009 Jan;1152:209-214

Zeniou-Meyer M, Béglé A, Bader MF, Vitale N
The Coffin-Lowry Syndrome-associated Protein RSK2 Controls Neuroendocrine Secretion through the Regulation of Phospholipase D1 at the Exocytotic Sites. Ann N Y Acad Sci., 2009 Jan, 1152:201-208

Seminar: cAMP-dependent activation of rhodopsin gene transcription in embryonic rods - Pierre Voisin (Poitiers)

February 16, 16:30 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Seminar: L'horloge biologique : une cible de choix pour les protocoles anti-vieillissement ? (presented in French) - Fabienne Aujard (UMR7179 CNRS & MNHN, Brunoy)

February 4, 14:00 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Seminar: How to find new drugs for CNS diseases - Jens Mikkelsen (Neurosearch A/S, Danemark)

February 4, 11:00 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Mendoza J, Pévet P, Challet E
High-fat feeding alters the clock synchronization to light. J Physiol., 2008 Dec 15, 586(Pt 24):5901-10

Corinne Liégeois rewarded by a Price from the association France-Alzheimer.

Nicolas Vitale rewarded by a Gutenberg Price from the Cercle Gutenberg - Alsace.

Aurélie Béglé rewarded by a Thesis Price from the Biology Society of Strasbourg

Handing-over of the prices: December 18 - European Doctoral College, 46 Boulevard de la Victoire, Strasbourg

Thesis: Mécanismes cellulaires et moléculaires impliqués dans la restriction temporelle de la synthèse de mélatonine dans la glande pinéale du hamster syrien - (presented in French) - Anthony Salingre

November 28, 14:00 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Thesis: Plasticité de la transmission synaptique inhibitrice dans le système nociceptif spinal de la souris - (presented in French) - Mathieu Rajalu

November 28, 14:00 - Atrium, amphithéâtre AT9, 16 rue Descartes, Strasbourg

Workshop : Astrocyte-Synapse Interactions

January 23 2009 - European Doctoral College, 46 Boulevard de la Victoire, Strasbourg

Free registration - Deadline: 15 December 2008

Informations and registration

Etienne Challet, leader of the group "Genesis and synchronization of circadian and seasonal signals", winner of the annual prize, Alsace committee of the Fondation pour la Recherche Médicale.

Awards ceremony: November 27

Poster | Program (in French)

Charlet A, Lasbennes F, Darbon P, Poisbeau P
Fast non-genomic effects of progesterone-derived neurosteroids on nociceptive thresholds and pain symptoms. Pain, 2008 Jul 7, 139:603-609

Benbouzid M, Choucair-Jaafar N, Yalcin I, Waltisperger E, Muller A, Freund-Mercier MJ, Barrot M
Chronic, but not acute, tricyclic antidepressant treatment alleviates neuropathic allodynia after sciatic nerve cuffing in mice. Eur J Pain, 2008 Nov, 12(8):1008-17

Seminar: Horloge circadienne et pulsatilités hormonales (presented in French) - Isabelle Bur (Montpellier)

October 31, 16:00 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Products demonstration by Millipore

October 21, 10:00-17:00 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Fourcaudot E, Gambino F, Humeau Y, Casassus G, Shaban H, Poulain B, Lüthi A
cAMP/PKA signaling and RIM1alpha mediate presynaptic LTP in the lateral amygdala. Proc Natl Acad Sci U S A., 2008 Sep 30, 105(39):15130-5

Seminar: Les canaux ioniques de la sensibilité cutanée (presented in French) - Marcel Crest (Marseille)

October 29, 11:00 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Seminar: Réseau locomoteur et courant sodique persistant (presented in French) - Frédéric Brocard (UMR 6196, Marseille)

October 8, 08:30 - IPCB, 21 rue Descartes, Strasbourg

Workshop: Oscillating phenomena: time to tick

November 19, 09:30 - Strasbourg

> Apply here

Thesis: Rôle et régulation de la dynamique des lipides au cours de l'exocytose régulée : implication de la GTPase ARF6 et de RSK2 (presented in French) - Aurélie Béglé

September 26, 14:00 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Thesis: Neuronal death mechanisms in cerebellar Purkinje cells (presented in English) - Stéphane Heitz

September 22, 14:30 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Hanon EA, Lincoln GA, Fustin JM, Dardente H, Masson-Pévet M, Morgan PJ, Hazlerigg DG
Ancestral TSH mechanism signals summer in a photoperiodic mammal. Current Biology, 2008 Aug 5, 18(15):1147-52

Seminar: Molecular determinants governing sterol-sphingolipid-protein interactions - Elina Ikonen (University of Helsinki)

September 11, 14:00 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Seminar: Niemann Pick disease type A: understanding the role of sphingolipids in neuronal physiology and pathology - Maria-Dolores Ledesma (Madrid)

September 11, 11:00 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Thesis: Role of membrane rafts in glia-induced synapse development - Renaud Thiebaut

September 12, 14:30 - Centre de Neurochimie, 5 rue Blaise Pascal, Strasbourg

Seminar: Combining electrophysiology and imaging to explore neural networks
Agnès Bonnot (CNRS-Univ Paris 6)

September 12, 14:00 - IPCB, 21 rue Descartes, Strasbourg

Seminar: The in vitro spinal cord preparation isolated from immature rodents as a model to investigate the development of locomotion
Laurent Vinay (CNRS Marseille)

September 11, 14:00 - IPCB, 21 rue Descartes, Strasbourg

Training: Electrophysiology Summer School

September 8-13, IPCB, 21 rue Descartes, Strasbourg